Saturday, May 26, 2007

What Are The Four Stages of Mesothelioma Cancer?



by: David Arnold Livingston

One rare form of cancer is called Mesothelioma, a malignant tumor in the mesothelial tissues of the lungs and the abdomen, arising from the inhalation of asbestos. Its rarity is one of the reasons why a lot of people are not aware of this kind of fatal disease. In fact, many people die of Mesothelioma undiagnosed. Although there is now a growing awareness of the hazards of asbestos to health, still many have not heard of Mesothelioma and thus, have not understood its nature, cause, signs and treatment. Even some physicians find it hard to detect Mesothelioma because its symptoms are akin to other diseases like lung cancer and pneumonia. Furthermore, it takes decades for a patient who was exposed to asbestos to develop Mesothelioma — fifty years, at most.

Being unaware of Mesothelioma poses higher risks since it deters diagnosis and treatment. A person undergoing treatment must know the different stages of the cancer or the extent of the disease. Chances of recovering from Mesothelioma and the kind of treatment depend on the stage of the illness. There are basically two staging systems used for Pleural Mesothelioma (lungs): TNM system and Brighan system. These staging systems are also used in other kinds of cancers; however, the first is commonly used. There is no established method in determining the stage of the Peritoneal Mesothelioma cancer (abdominal) so the TNM system is used.

There are three variables in the TNM system: tumor, lymph nodes and metastasis. In the earliest stage of Mesothelioma, stage I, the malignant Mesothelioma cells start to grow and multiply only one layer of the pleura. The pleura is the membrane that encloses the lungs and lines the wall of the chest cavity. However, there are some instances wherein the pericardium (membrane that covers the heart) and diaphragm cover are already affected. In this case, the cancer patient is still in stage I Mesothelioma.

In the second stage, the two layers of the pleura are already affected by Mesothelioma. Take note, however, that in this stage, only one side of the body is affected. Normally, the pleura produces only small amount of lubricating fluid that allows easy expanding and contracting of the lungs. The excess fluid is absorbed by the blood and the lymph vessels so there’s a balance between the amount of fluid produced and removed. During the second stage Mesothelioma, fluid starts to build up between the membrane of the lungs and the membrane of the chest wall, resulting to pleural effusion. The increase in the volume of fluid produced causes shortness of breath and chest pain. Other Mesothelioma cancer patients experience dry and persistent cough. Diagnosis of the pleural effusion is achieved through a chest x-ray.

Stage III Mesothelioma means that the malignant cells have already spread to the chest wall, esophagus and the lymph nodes on one part of the chest. The patient may suffer severe pain near the parts affected. When not treated immediately or when the Mesothelioma patient doesn’t respond well to medication, the cancer may advance to the fourth stage. The fourth stage Mesothelioma is formidable since at this stage the Mesothelioma cells have penetrated into the bloodstream and other organs in the body like the liver, the bones and the brain. The lymph nodes on the other side of the chest may also be affected by Mesothelioma in stage IV.

Brighan staging system, on the other hand, determines whether the Mesothelioma can be surgically removed or not and whether the lymph nodes are affected or not. In stage I Mesothelioma, the lymph nodes are not yet affected and the patient can still recover through surgery. In stage II, surgery can still be executed but some lymph nodes have already been infiltrated by the cancer cells. In stage III, the heart and chest wall are already affected; thus, surgery is no longer advisable. The lymph nodes in this stage, however, may or may not be affected. In the final stage, stage IV Mesothelioma, cancer cells have already gone to the bloodstream and other parts of the body like the heart, brain, bone and liver. In most cases, a patient who has reached stage IV Mesothelioma only has four to twenty-four months to live.

Source: http://www.articlecity.com/


Wednesday, May 16, 2007

Mesothelioma - An Asbestos Related Lung Cancer



by: Jill Kane

What is Mesothelioma?

Mesothelioma is a form of cancer located in the lining of either the lungs, abdomen or the heart. These linings are thin layers of tissue covering the organ.

The pleura is the tissue covering the lungs and the wall of the chest cavity which cushions and protects the lungs. The peritoneum lines the abdominal wall and surrounds most of the organs in the abdomen. The pericardium is the tissue surrounding the heart.

Mesothelioma is a rare but very serious cancer. There are three types of mesothelioma based on the types of cancerous cells. The most common type is epithelioid and consists of 50-70% of total cases and has the best prognosis. The second type is called sarcomatoid, consists of 10-20 % of mesothelioma cases and is more unpredictable in nature. The third type of mesothelioma is called biphasic, it is a combination of the other two types and consists of 20-35% of all cases.

There are an estimated 2000-3000 new cases of mesothelioma in the United States every year. The majority of these cases begin in the chest wall (pleural mesothelioma), a few start in the abdomen (peritoneal mesothelioma) and very rare are the cases starting in the lining surrounding the heart (pericardial mesothelioma).

The pleura is a thin lining of mesothelial cells. There are two pleuras in the chest, the parietal pleura and the visceral pleura. The parietal pleura lines the chest wall including the inside of the ribs, diaphragm and pericardium. The visceral pleura covers the lungs and filters fluid to and from the chest. If the pleura becomes diseases it is not effective at eliminating fluid from the chest resulting in pleural effusion or too much fluid in the chest.

Mesothelioma is usually the result of exposure to asbestos. Most people who are diagnosed with mesothelioma have had jobs where they breathed asbestos fibers. It may take up to 60 years from the time of asbestos exposure until mesothelioma develops.

Although rare, mesothelioma is a serious form of cancer which is often in its advanced stage when a diagnosis is made. In general, prognosis for mesothelioma patient is poor, however, some patients live with the disease for a long time. As mentioned earlier, the type of mesothelioma has an impact on the prognosis, as well as, the age of the patient, how much tumor has developed and if treatment is rendered. There are many variables in evaluating a mesothelioma case, so only the patients doctor can determine the best treatment and possible prognosis on an individual basis.

Source: http://www.articlecity.com/


Wednesday, May 2, 2007

Mesothelioma Cancer



by: P. Mehta

Mesothelioma is a type of cancer involving mesothelial tissues of body organs usually lungs or abdominal. It is often caused by exposure to asbestos. However, there are 30-50% of patients without any history of asbestos exposure. People who have received asbestos exposure of as little as one or two months to very low doses are at risk of mesothelioma cancer. Even people who wash clothes of asbestos exposed people are at risk. A person exposed to asbestos could develop mesothelioma after 50 years of exposure.

People in the occupations such as construction jobs in shipyards, insulators, boilermakers, etc. are at the risk of contracting asbestos disease.

The 2 common types of mesothelioma are:

Pleural mesothelioma (lung cancer) and Peritoneal mesothelioma (abdomen organs). The survival time for a patient with diffuse malignant mesothelioma is from 4 to 24 months from the observance of the symptoms. Mesothelioma is also difficult to diagnose.

The chance of recovery for a patient with mesothelioma depends on size and location of the cancer, age of the patient and his response to the treatment. Presently, the treatment options for mesotheliomas are:

Radiation therapy, Chemotherapy, Surgery and Photodynamic therapy. There is some evidence that provitamin A or beta-carotene may decrease the risk of mesothelioma.

Source: http://www.FatFreeKitchen.com


Tuesday, May 1, 2007

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